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pentobarbital will lessen the extent or influence of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Robust or average CYP3A4 inducers may possibly maximize rate of diazepam elimination; as a result, efficacy of diazepam could be reduced.pentobarbital will lower the level or influence of ibuprofen by a

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